The EF equation entails:
– That reduced diastolic chamber dimension (reduced EDV) will alter EF – progressive blood loss will often reduce EDV and thus increase the EF
– When EF increases – under these circumstances – the stroke volume will decrease concomitantly
– Thus the EF can go up to almost 100% without providing any clinically useful information about myocardial deformation or adequacy of circulation
– Recognition of the hypovolaemic state is the key to understanding and solving the problem in these patients

